Will artificial intelligence find the cure for what ails us? AI pioneer Daphne Koller is betting it will—at the very least—supercharge the hunt for new drugs. In this issue, Koller explains the strategy behind her AI-first company, Jon Webster explores how generative AI is reshaping work and Priti Singh asks where companies are headed with equity diversity and inclusion. Daphne Koller wants to revolutionize drug discovery As co-founder of Coursera, Daphne Koller transformed the landscape of online learning. With insitro, she’s aiming even higher, with a goal to disrupt longstanding approaches to drug development. She breaks down her strategy in this Institute Dialogue with Paul McCracken, CPP Investments’ Managing Director Growth Equity and Nadeem Janmohamad, Managing Director Active Equities North America. Watch here “There’s a danger of giving up on generative AI” As CPP Investments’ Chief Operating Officer, Jon Webster is on the front lines of the technological change reshaping global investing. In the latest episode of the Technovation podcast, he reflects on the democratization of technology, the “heart of data security”, and how generative AI will reconfigure work. Read it here CPP Investments' Net Zero commitment: The Harvard case study Harvard Business School explores CPP Investments’ commitment to reach net zero emissions by 2050. The decision placed it among a decidedly small group of global asset owners (around 7%). It also drew criticism. In this excerpt, President and CEO John Graham and Chief Sustainability Officer Richard Manley reflect on the move. Read more Beyond the backlash: What’s next for EDI? Tight labour markets and shifting demographics are fuelling corporate efforts to find effective EDI strategies—even as the issue becomes politicized. Priti Singh, CPP Investments’ Senior Managing Director and Global Head of Capital Markets and Factor Investing and Diana Scott, Center Leader, U.S. Human Capital Center at The Conference Board break down the business case for EDI. Read more Earnings season to test post-pandemic market rally —Varun Sharma, Managing Director, Exposure Management, Total Fund Management The FANGs. The FAANGs. The Magnificent 7. American tech stocks have all but dominated headlines over the last year—with each new group generating a fresh buzz-worthy name. The latest classification of highfliers? The Fab Four—Nvidia, Amazon, Meta, Microsoft. As we look to the next fiscal year, it’s worth taking a step back to compare performance against the hype. Read more In case you missed it How are investors navigating the AI era? Find out in a new World Economic Forum Agenda blog by Judy Wade, Managing Director, Head of Strategy Execution and Relationship Management and Chris Gillam, Director Operational Risk and WEF Fellow. John Graham explains how a strong, stable resilient pension fund can help shape the future—particularly in countries facing demographic challenges. Read his blog for the Milken Global Institute. CPP Investments’ total portfolio approach builds resiliency in turbulent times. Read this excerpt from Innovation Unleashed, a new report from the Chartered Alternative Investment Analyst Association (CAIA).